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At this point, one must continuously consume the substance to stave off the unpleasant withdrawal symptoms, an important part of addiction known as dependence

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Around 1560, Jean Nicot, the French ambassador to Lisbon, popularised the use of tobacco leaves as a cure for carcinoma and ringworm in the court of King Francis II of France

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This consolidation of CSR funds into fewer organizations may suggest that PMI is becoming more discerning in its CSR focus areas or attempting to create the perception of a more substantial impact with its contributions