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As the report notes, the elimination of tobacco use and its unequaled harms is now within our grasp, but achieving this goal will require significant scientific progress, including advances led by the NCI. Further, the report says that the research community must consider key factors that help maintain continued tobacco use, including a changing population of tobacco users, evolving patterns of tobacco use, new and different tobacco products, and a complex and rapidly evolving policy environment

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The tobacco Euro-Americans used for trade originated in the Andes of South America, where the domestication process began as much as 8,000 years ago

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