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A similar metabolic response was observed by McGregor et al

Alpha Lipoic Acid: This ingredient works synergistically with Glutathione to detoxify the skin, enhance skin brightness, and improve overall skin health

N Engl J Med 2013;369(14):13061336

(2015) 'Randomised, Placebo-Controlled Trial of Methyl B12 for Children with Autism', *Journal of Autism and Developmental Disorders*

In a randomized controlled trial in 64 people with a history of calcium oxalate kidney stones, three years of potassium-magnesium citrate supplementation providing about 255 mg of magnesium resulted in an 85% reduction in kidney stone risk compared with placebo (Ettinger 1997)