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Results The p53 TAD2 region plays a crucial role in the interaction with FOXO4 FHD Interactions between FOXO4 and p53 in the nucleus have been reported to promote cellular senescence 34

bone marrow aspiration or bone marrow biopsy may be recommended in some cases to examine for the presence of bone marrow disorders

Swelling around the joints Not everyone experiences dramatic swelling

It will therefore be important to determine whether a different dosing regimen might allow administration of significantly fewer doses without compromising accelerated fracture repair (Fig

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