In the latter experiment, stable re-expression of wtIDH1 rescued IDH1/ PC cells (i.e., promoted chemotherapy resistance), while the catalytically-altered mtIDH1 did not
Meziani MJ, Dong X, Zhu L, Jones LP, LeCroy GE, Yang F, et al
Possible B12 injection side effects tend to be mild and short-lived, and may include: Injection site pain, redness, or swelling Mild itching Brief diarrhea (less common) A feeling of warmth after the injection Serious side effects are rare
The injectable route ensures adequate B12 delivery regardless of gut function
2.2.2 Secondary metabolites Flavonoids, phenolic acids, alkaloids, and terpenoids are often modulated, which can influence plant defense, nutritional quality, and aroma profiles (Zhang et al., 2024a, 2024b)