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The inclusion of proper controls (negative and positive controls) as well as preventive/protective versus treatment (i.e., treatment with urolithin A before versus after exposure) of sleep disturbances and disorders designs should be considered to evaluate potential benefits of urolithin A in the prevention and management of sleep conditions and their downstream adverse health effects

mean increases in resting heart rate of 1 to 4 beats per minute (bpm) were seen with routine clinical monitoring in semaglutide-treated patients vs