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Yes, ultraviolet and fluorescent light cause oxidative damage to methionine and tryptophan residues in IGF-1 LR3, which compromises receptor binding affinity even in lyophilised form

Mambo E, Gao X, Cohen Y, Guo Z, Talalay P, Sidransky D

Al-Hakeim HK, Al-Rubaye HT, Almulla AF, Al-Hadrawi DS, Maes M

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84 The overexpression of circHECTD1 leads to increased expression levels of p62, ATG5, and ATG9 via the inhibition of miR-182-5p, which activates AMPK/mTOR signaling and reduces colonic injury and inflammation by promoting autophagy