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10.1002/rcm.3329 79 StrangeR

The PRMT5 inhibitor PF-06939999 inhibited the proliferation of non-small cell lung cancer (NSCLC) in cells and animal models and dose-dependent reduced symmetrical dimethylarginine (SDMA) levels

In RA model, some natural medicines (such as resveratrol, baicalin and -mangiferin) antagonize the transcriptional activity of NF-B by up-regulating the expression of SIRT1, thereby inhibiting the expression of a variety of inflammatory cytokines (such as TNF, IL-6 and IL-1), and inhibiting the proliferation, invasion and migration of FLSs, which has a positive effect on RA

MATERIAL AND METHODS Three iodine products were tested