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This increased -lactam reactivity is explained by the R 2 substituent that may act as a leaving group ( In biological settings and biochemical research, low molecular weight thiols are important antioxidants, which act through a variety of mechanisms

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Chondrocytes are involved in maintaining the integrity of the extracellular matrix and controlling the balance of articular cartilage homeostasis, thereby contributing to the deceleration of OA development (158, 159)