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Availability of data and materials The datasets analyzed during the current study are available in the IPUMS repository at Abbreviations NHIS: National health interview survey HR: Hazard ratio CI: Confidence interval IPUMS: Integrated public use microdata series NDI: National Death Index ICD: International classification of diseases and related health problems BMI: Body mass index CPS: Cancer prevention study TUS-CPS: Tobacco use supplement to the current population survey References Rostron BL, Corey CG, Gindi RM

JAMA Psychiatry

They include diacetyl, the chemical blamed for causing "Popcorn lung" in workers at microwave popcorn packaging plants, and formaldehyde, known to cause cancer

2 weeks to 3 months later Heart attack risk dramatically drops

It is known to induce CYP3A4 and CYP2C8/9 enzymes, starting within 4 days of the first dose and returning to baseline 14 days after discontinuation