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Overall, these findings suggest that ATXN3 aggregation may target directly or indirectly a metastable subproteome, thereby causing an increased susceptibility to multifactorial toxicity and, eventually, the collapse of many essential cellular functions, and this may help to explain the phenotypic complexities displayed in SCA3

JAMA 2014;312:380-389

Storage requirements Lyophilized (powder) 20C up to 24 months Reconstituted 28C up to 14 days Literature Peer-reviewed research for laboratory background The Lancet 2021 PMID 34481571 Lau DCW et al

Mixing peptides together can destabilize both compounds and reduce effectiveness