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87 Notably, GSH protection against antibiotics did not require the AcrAB pump but failed in cells lacking the TolC channel, 88 suggesting that TolC-dependent pumps are involved

A study showed that increased plasma iron levels in FPN mutant mice led to decreased osteogenesis, indicating a negative regulatory role of ferroportin in osteoclasts (86, 87)

As a result of increased oxidative stress, cerebral diseases such as brain damage or epilepsy occur 39,40