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Some formulations may require refrigeration

Keeping the medication cold helps maintain its potency and prevents the breakdown of the peptides

May convince skeptical physician if clear objective improvements documented

But given that some multivitamins dont contain enough B12 to meet our minimum recommendations, Im sympathetic to the idea that it could be dangerous for vegan health professionals, and the greater vegan community, to promote the idea that for B12 vegans can just take a multivitamin. After the discussion with my colleague and reviewing the research, I see a need for vegan advocates to emphasize that when relying on daily multivitamins as a sole source of B12 vegans need to make sure it meets our minimum recommendations

Copper serves as a key enzymatic cofactor for pathways involved in collagen and elastin maturation (cross-linking) , antioxidant defense , and broader tissue remodeling