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The following antibodies were used for ChIP assay: anti-ACTL6A (Abcam, ab3882), anti-NRF2 (Cell Signaling Technology, 12721 s), and Rabbit IgG (ab37415) (Abcam, Cambridge, MA)

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Data entry was done in Microsoft Excel and descriptive statistics was applied

[1] [5] Meta-analyses suggest kava can reduce anxiety symptoms sometimes comparably to medications like oxazepam and buspirone with strongest evidence seen in multiweek studies using aqueous extracts for generalized anxiety disorder, although results were mixed and standardized trials are limited

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