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Leaky Gut and Neuroinflammation BPC-157 acts as a membrane stabilizer, counteracting increased intestinal permeability (leaky gut syndrome) associated with depression pathophysiology, cognitive dysfunction in schizophrenia, and breakdown of paracellular pathways in deficit schizophrenia

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CIRP Annals , 68 , 237240

While this seems counterintuitive (you might expect less side effects from weaker medication), degraded peptides with altered structures can sometimes trigger different inflammatory responses at the injection site