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Similarly to if you eat healthy for a week, you may not feel any different even though you will certainly be improving your health.

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Through multi-target mechanisms, these active metabolites either directly activate the -catalytic subunit of AMPK (via phosphorylation at Thr172) or indirectly modulate upstream kinases (such as LKB1 and CaMKK ), thereby influencing the expression and activity of downstream key effector molecules, including ACC, SREBP-1c, and PPAR

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