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Tobacco use makes the heart work harder and increases the likelihood of cardiovascular issues

Because they are not made from tobacco leaves, many companies market their nicotine pouches as tobacco-free or as a less harmful alternative to smoking or traditional smokeless tobacco products

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January 21, 2023

70 A modified risk tobacco product (MRTP) is defined as "any tobacco product that is sold or distributed for use to reduce harm or the risk of tobacco-related disease associated with commercially marketed tobacco products." 71 For example, some ENDS manufacturers may decide to submit an ENDS product through the MRTP pathway if the application can justify that the product reduces the risk of tobacco-related disease compared with other tobacco products (e.g., cigarettes)