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[DOI] [PMC free article] [PubMed] [Google Scholar] Santesmasses D

A., Olynyk, J

The key signaling pathways investigated include the nuclear factor erthriod 2 related factor 2 (Nrf2) activation cascade which leads to the upregulation of phase 2 detoxification genes heme oxygenase (HO1), superoxide dismutase and catalase (CAT), inhibition of the inflammatory signaling pathway of nuclear kappa B (NF-B), modulation of PI3K/Akt/mTOR pathways in cancer cells and activation of the adenosine monophosphate activated protein kinase (AMPK) for metabolic regulation

J Diabetes Complicat 19:247253 Villegas-Rivera G, Roman-Pintos L, Cardona-Munoz E et al (2015) Effects of ezetimibe/simvastatin and rosuvastatin on oxidative stress in diabetic neuropathy: a randomized, double-blind, placebo-controlled clinical trial

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